Our Commitment
Our Five Commitments
Developed by
a physician
100% natural
cod-skin collagen
Made in Japan
No preservatives
or colorings
Careful quality
control
The source of that vitality lies in the suppleness of the “inner pathways” that run throughout our bodies.
The foundation that supports our bodies is made up of collagen and elastin.
However, as the quality of this foundation changes with age, it can also affect the condition of the whole body.
“Smoothly, without stagnation”
To keep protecting this everyday well-being, it is essential to replenish high-quality collagen
and maintain a resilient cycle from within.
The basis of good health is well-maintained inner infrastructure. It is because of a supple, flexible
foundation that nutrients can reach every corner and the whole body brims with vitality.
“A spring-like bounce, from within”
Supporting a healthy cycle in which old and new collagen are replaced in a steady rhythm,
for days that flow without stagnation!
Order Here!
We recommend one sachet a day, continued for two months.
Jelly-like texture with a yuzu and honey flavor ♪
1 bag (28 sachets)
Regular price ¥6,000 (excl. tax)
Price¥6,600 (tax incl.)
Ordering from outside Japan? See our International Shipping Guide
Buy NowAbout Collagen
About 30% of the protein that makes up the body is collagen.1
01
Collagen is a fibrous protein that forms many tissues of the body, such as skin, bone, tendons, cartilage and blood vessels.
How much collagen each tissue contains
02
Data comparing skin collagen by age show a peak at 25–34, followed by a gradual decline of about 25% by 65–74. Another study of 76 women by decade found a significant decrease after the 40s.6,7
Skin collagen by age7
Over 4 decades~25%lower
Values are “Percent collagen score” (n = 64). Ages 25–34 and 65–74 are from the text; others are read from the figure. The original data come from a collagen ingredient manufacturer’s laboratory.
*Research findings do not indicate the effects or efficacy of any product.
Derived from cod skin, tempered by
the cold, rough waves of the North Atlantic
Derived from the bonito bulbus arteriosus,
which supports the cycle of life in the Indian Ocean
Dr.Energy Collagen EX was designed with a focus on the blend ratio
of collagen and elastin. This ratio is modeled on the balance of collagen
and elastin found in human connective tissue.
For this product, we were particular about our collagen and elastin raw materials from the very first stage of selection. For collagen, we use 100% natural cod skin, and we never use fish scales or salmon skin, as they are of lower quality. We chose our materials with careful attention to their origin and processing methods. For elastin, we use 100% natural bonito bulbus arteriosus.
For this product, we developed the formulation based on the characteristics of the raw materials and their processing steps. For elastin, too, we use naturally derived raw materials, with careful consideration of how it combines and balances with collagen.
Collagen comes from many sources, such as cattle, pigs and fish. Using Japanese government statistics, we compared how much antimicrobial (antibiotics, etc.) is used for each.
Pigs (skin)363
Farmed fish(salmon, tilapia, etc.)192
Cattle (hide, bone)95
Wild cod (skin)0None usedSource: MAFF National Veterinary Assay Laboratory, sales of veterinary drugs, 2024 (farmed fish = marine aquaculture; wild-caught fish receive none)
Raw materials from countries with BSE are subject to import rules
Antimicrobial use varies greatly by country: Norway about 0.5 t (2023), Chile about 351 t (2024)
A study of farms in China found antimicrobials in feed and pond sediment
Dr.JAPAN chooses the skin of wild cod from the North Atlantic,
raised without antimicrobials.
*This compares raw materials and does not indicate the effects of any product. Sources: “Wild vs. Farmed Fish” / MAFF sales data / NORM-VET 2023 / Farias et al. 2025 / Zhou et al. 2021 / MHLW (BSE)
Collagen differs by source. Here is how the natural cod skin we use compares with other common sources.
| Our raw materialNatural cod skin | Fish scales | Pig skin | Cattle hide & bone | |
|---|---|---|---|---|
| Origin | North Atlantic (wild) | Varies by product | Varies by product | Varies by product |
| Denaturation temperature | about 18–22°C | about 24–37°C | about 41°C | about 35–40°C |
| BSE-related import rules | None | None | None | Yes (depends on the part) |
| Demineralization step | Not needed | Needed | Not needed | Needed for bone |
*Temperatures are from published studies and vary with species and method. This compares raw materials and does not indicate the effects of any product. Sources: “What Is Fish Collagen?”
Fish collagen comes from many kinds of fish. Here is why we choose natural cod skin, compared with other common fish.
| Our raw materialNatural cod skin | Atlantic salmon skin | Tilapia skin & scales | |
|---|---|---|---|
| On Japan’s recommended allergen-labeling list | No | Yes (salmon) | No |
| Wild or farmed | Wild-caught Global catch: about 954,000 t (2023) | Almost all farmed Farmed: over 2.8 million t; wild catch: about 1,248 t (2023) | Mainly farmed About 5.3 million t worldwide (2022) |
| Demineralization step | Not needed | Not needed | Skin: not needed; scales: needed Calcium in scales is dissolved with hydrochloric acid, etc. |
| Dr. Hikaru Ishii’s research (patent, paper) | Used natural cod skin collagen | — | — |
*Allergen labeling shows only whether the fish is on the recommended list; it does not mean no allergy can occur. People with fish allergy should take care. This compares raw materials and does not indicate the effects of any product. Sources: “What Is Fish Collagen?” / Consumer Affairs Agency, allergen labeling / EUMOFA Atlantic cod / EUMOFA Atlantic salmon / FAO SOFIA 2024 / Feng et al. 2015 (scale demineralization)
Collagen from fish scales requires a step called demineralization. Fish scales are made of hydroxyapatite (the calcium mineral also found in bone) and collagen fibers. To extract collagen from scales, this calcium must first be dissolved and removed. This step is called demineralization.
Scales
Our raw materialNatural cod skin
The natural cod skin we use has no calcium layer like scales do, so collagen can be extracted without a demineralization step that dissolves calcium with hydrochloric acid or other chemicals.
*This describes how raw materials are processed and does not indicate the effects of any product. Source: Feng et al. (2015), J Food Sci Technol
Elastin also differs by source. Here is how the skipjack bulbus arteriosus we use compares with other common sources.
| Our raw materialSkipjack bulbus arteriosus | Pig | Cattle | Chicken | |
|---|---|---|---|---|
| Wild or farmed | Wild-caught | Livestock | Livestock | Livestock |
| Habitat | Warm open waters of the Indian Ocean (15–30°C) | Raised as livestock | Raised as livestock | Raised as livestock |
| BSE-related import rules | None | None | Yes (cattle-derived) | None |
*This compares raw materials and does not indicate the effects of any product. Sources: “What Is Elastin?”
Why we choose the skipjack bulbus arteriosus as our elastin source.
We use wild-caught skipjack. About 3.2 million tonnes are caught each year, the most of any tuna.
For cattle- and pig-derived materials, concerns have been raised about diseases that pass from animals to people, such as BSE and foot-and-mouth disease. Fish-derived materials are used as an alternative.
The bulbus arteriosus at the outlet of the heart is reported to be rich in elastin. It is a by-product of processing.
*This describes the raw material and does not indicate the effects of any product. Sources: “What Is Elastin?” / Cai WW et al., Mar Drugs 2022 / Gaikwad S, Kim MJ, Mar Drugs 2024
Ms. A (50s)
My lower back and knees feel easier, and my body feels lighter! I feel as if my body has become younger, and I enjoy exercising.
I also feel that my hair has increased. I'm glad I started.
Ms. B (80s)
It's a jelly, so it's easy to eat, and it tastes good. My skin gained firmness, and my hair gained body and bounce! I'm happy that people think I look younger than my actual age!
*Individual results; personal impressions.
¥600 (tax included; flat rate anywhere in Japan).
We will ship your order within one week after your payment has been confirmed.
Two years.
Yes, we do. Please see our International Shipping Guide page.
Physician / MD, PhD
Hikaru Ishii
Hikaru Ishii, MD, PhD, the developer of Dr.Energy Collagen EX, obtained an international patent on the prevention of arteriosclerosis using natural cod-skin collagen in 2011. In 2015, he reported a peer-reviewed paper on the improvement of carotid arteriosclerosis. He is currently conducting a clinical study for a U.S. patent application on bust enhancement.
Our fish-skin collagen is based on
academically recognized, peer-reviewed papers!
Order Here!
We recommend one sachet a day, continued for two months.
Jelly-like texture with a yuzu and honey flavor ♪
1 bag (28 sachets)
Regular price ¥6,000 (excl. tax)
Price¥6,600 (tax incl.)
Ordering from outside Japan? See our International Shipping Guide
Buy Now