Advancing healthy longevity and beauty science — Dr. Hikaru Ishii, MD, PhD


An ECM-based approach grounded in natural fish skin collagen research

Extend healthy lifespan,support lasting beauty.

Dr. Hikaru Ishii

Chairman Dr. Hikaru Ishii, MD, PhD

Dr.JAPAN focuses on extracellular matrix (ECM) health, supporting vibrant living through clinical research on natural fish skin collagen and evidence-based supplement development.

NK Cell-kun
Dr. ACIS Dr. Energy Collagen EX
Decolla(デコラ)新発売・数量限定

New Launch · Limited Quantity

30 years of Dr. Ishii’s collagen research, realized

Decolla

Beauty and health are two sides of the same coin.

Everyone wants to feel beautiful. Everyone wants to stay healthy.
After three decades pursuing both wishes, Dr. Ishii arrived at the Ishii Theory: beauty and health are inseparable.
From that theory and research comes Decolla — a collagen supplement designed for women.

Limited launch from late August Thirty years of collagen research in one formula.
Planned price ¥6,000 (excl. tax) 28 sachets
No hormone-like ingredients Quality designed for daily, confident use

What is Decolla?

Not just a catchy name. Decolla is a high-quality collagen supplement for women, developed from Dr. Ishii’s 30 years of collagen research — including European patent technology and peer-reviewed academic publications.

Key ingredients

  • Premium, high-dose natural cod skin collagen
  • Premium, high-dose elastin from bonito arterial bulb
  • Calcium

A carefully balanced formula to support daily beauty and wellness nutrition.

The men’s sister product Dr.Energy is available via Alter membership sales.

What's New

2026/06/05Notice
Clinical information has been added to our website.
2025/01/29Notice
Our website has launched.

About Dr.JAPAN

Dr.JAPAN Co., Ltd. is dedicated to advancing healthy longevity and beauty science through rigorous clinical research on natural fish skin collagen.

Our founder, Dr. Hikaru Ishii, brings over 54 years of clinical experience, including a European patent for collagen-based vascular health, 17 years of NK cell immunotherapy (634 cases), and more than 50,000 gastrointestinal endoscopic procedures.

Guided by the hypothesis that healthy longevity and beauty share the same biological foundation — the extracellular matrix (ECM) — we develop evidence-based supplements for people worldwide.

Publications by Dr. Hikaru Ishii

About our publications and sales figures

If Your Blood Vessels Stay Young, Your Healthy Lifespan Extends

If Your Blood Vessels Stay Young, Your Healthy Lifespan Extends

Gentosha Publishing

12,000 copies sold

The Lies of Doctors

The Lies of Doctors

Gentosha Publishing

120,000 copies sold

The Doctor's Crime and Punishment

The Doctor's Crime and Punishment

Gentosha Publishing

8,000 copies sold

ANK — Immune Cell Therapy When Diagnosed with Cancer

ANK
Immune Cell Therapy When Diagnosed with Cancer

Gentosha Publishing

8,500 copies sold